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Imaging mass spectrometry device Product List

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[Analysis Case] Component Analysis of Hair Roots

Visualization of biological components such as cholesterol and fatty acids using TOF-SIMS.

The hair roots of human hair (both shed hair and pulled hair) were pressed against a Si wafer, and imaging measurements (surface analysis) were conducted on the transferred components. Shed hair shows a strong tendency for ■K and ●phospholipids to be present only at the tip of the hair root. Additionally, it is believed that the entire hair root contains ■CnHmCOOH (n=17–31) fatty acids (derived from human sebum), ●amide components derived from keratin plugs, ◆nitrogen-containing organic acids with a mass of 500–700, and ◆organic substances with a mass around 800 that are aggregated. However, the organic substances containing two COOH groups derived from human sebum, which are observed in pulled hair, show a weak tendency.

  • Contract Analysis
  • Imaging mass spectrometry device

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rapifleX MALDI TOF(/TOF)

rapifleX will revolutionize the common understanding of MALDI imaging measurements.

**Features** - Rapid analysis at 50 pixels/second with clear images - Improved pixel reproducibility with 10kHz smartbeamTM 3D - Spatial resolution with pixel size <5μm enables more advanced information exploration - Durability significantly enhanced by a newly designed ion source - Wide dynamic range achieved with a 10-bit digitizer - MS/MS mass range up to 8 kDa - 3-stage gridless design: uncompromising maximum resolution across the entire molecular weight range

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